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Roemhild K, von Maltzahn F, Weiskirchen R, Knchel R, von Stillfried S, Lammers T (2021) Iron metabolism: pathophysiology and pharmacology

Understanding Hyperpigmentation and Uneven Skin Tone Hyperpigmentation occurs when the skin produces excess melanin in certain areas

Leung EY, Crozier JE, Talwar D, et al

( b ) Beutler, E., and Duron, O., Transfusion , 5 , 17 (1965)

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Fe overload triggers direct mitochondrial membrane lipid peroxidation via Fenton reaction-derived hydroxyl radicals, while Cd impairs mitochondrial antioxidant defenses by suppressing glutathione peroxidase 4 (GPX4) activity
