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Among HF patients hospitalized with infections, including urinary tract infection, pneumonia, or sepsis, those with concurrent Clostridioides difficile infection (CDI) had higher in-hospital mortality than those without CDI [160]

Fertil Steril (2020) 113:374382.e2

The research by Nilaksh Gupta and colleagues found that iodomethylcholine (IMC) can inhibit the production of microbial TMA in hosts and reduce plasma TMAO levels, demonstrating over 10,000-fold greater potency (sub-nanomolar IC50) compared to previously reported microbial choline TMA lyase inhibitors (Gupta et al., 2020)

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In contrast, it is recommended to replace red meat with alternatives like fish and poultry, which not only provide high-quality protein but also help reduce the risk of chronic diseases