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tb 500

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doi: 10.1007/s10456-014-9420-y

Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity

A 2023 double-blind split-face study with 60 participants aged 40 to 65 compared a 0.05% GHK-Cu topical formulation to placebo over 12 weeks