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Description
Safety Profile and Contraindications While human clinical trials specifically for joint applications have not been conducted, AOD-9604 has been extensively studied in clinical trials for metabolic applications
It does not appear to affect IGF-1 levels or insulin levels and therefore is not a risk factor in promoting glucose intolerance or diabetes
The problem
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Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)
Clinical Pharmacology and Therapeutics
