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In fact, FMO1 is also participated in the oxidization of TMA to TMAO, however, its specific activity is only 1/10 that of FMO3 ( Numerous studies indicate that inhibition of FMOs, especially FMO3, is an effective target for reducing TMAO concentrations (Zhu et al., 2018

Colombani P, Wenk C, Kunz I, Kraehenbul S, Kuhnt M, Arnold M, Frey-Rindova P, Frey W, Langhans W

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Other studies, however, have found no significant effect of carnitine on weight loss in healthy individuals or athletes
