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Ethics approval and consent to participate The animal study was approved by the Ethic Committee approval Institutional is Shenzhen Graduate School of Peking University and the approval code is FYXK (No

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Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage

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In addition, it is well known that high levels of NH 3 induced by high amino acid intake have toxic effects, especially for the brain and the kidneys (Reference Conway and Hutson69,Reference Davani-Davari, Karimzadeh and Sagheb72)