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Description
A amyloidosis induces neuroinflammation and affects Tau pathologya microtubule-associated protein crucial for tubulin assemblyyet recent research indicates that these may represent separate clinical processes ( Current evidence indicates that cellular impacts occur years prior to the onset of clinical symptoms, with mitochondrial failure in neurones and astrocytes acting as a primary early indicator ( While A and Tau have been the main subjects of prior study, new data emphasizes mitochondrial breakdown and the ensuing oxidative stress as early, predictable events in AD pathogenesis

Epstein-Barr Virus latent membrane protein-1 triggers AP-1 activity via the c-jun n-terminal kinase cascade
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Nat Clin Pract Neurol

doi: 10.1016/j.atherosclerosis.2023.03.010 156 GarnerKMAminRJohnsonRWScarlettEJBurtonMD

, 2015, vol
