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The Journal of Endocrinology

VPA is thought to cause hyperammonaemia by 3 proposed mechanisms: (i) inhibition of CPS1 by VPA or 1 of its metabolites

doi: 10.1016/j.tem.2015.12.001 65 SongJEAlvesTCStutzBSestan-PesaMKilianNJinSHet al

Other exclusions apply

Clinical, biochemical and genetic analysis of Chinese patients with isobutyryl-CoA dehydrogenase deficiency

Este ltimo efecto an no se considera clnicamente relevante, ya que todos los estudios se han realizado in vitro
