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PMID: 27977392

Available from: Vosburg RW, El Chaar M, El Djouzi S, Docimo S, Choi D, LaMasters T et al (2022) Literature review on antiobesity medication use for metabolic and bariatric surgery patients from the american society for metabolic and bariatric surgery clinical issues committee

Adverse Effects Aside from the debated increased risk of DR progression, a separate complication that has garnered widespread attention is the purported association of semaglutide with an increased risk of NAION, a vision-threatening condition

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The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board