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A study of the gut microbiota composition of patients with more than 10 years of alcohol overconsumption showed a higher relative abundance of bacteria from phylum Proteobacteria and higher levels of the genera Sutterella , Holdemania , and Clostridium , and a lower relative abundance of bacteria from genus Faecalibacterium compared to control patients with no or low alcohol intake history (196)

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4.Preservation of Metabolic Homeostasis Unlike continuous GH presence, which can lead to insulin resistance through sustained lipolysis, pulsatile release maintains a balance between anabolic signaling and glucose sensitivity

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This leads to lactate accumulation and exacerbation of the Warburg effect, further aggravating hepatocyte injury, inflammation, and fibrosis, and driving the collapse of systemic lipid, glucose, and other metabolic processes (Cheng et al., 2025)

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AI has also shown notable advantages in diagnosing left ventricular hypertrophy (LVH)

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Paternal smoking as a cause for transgenerational damage in the offspring

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