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doi: 10.1016/j.expneurol.2014.04.008

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Chronic niacin deficiency leads to pellagra, a condition now rare in developed countries due to its association with poor nutrition, resulting from low intake of niacin or tryptophan (, , )

Notably, the compound is stable across a wide pH range and fully soluble in aqueous media, unusual properties for a peptide of this size that are attributed to its high proportion of proline and charged residues

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Otherwise, there is nothing notable about vitamin B12 and its side effects