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Design, synthesis, and characterization of a series of cytochrome P-450 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver

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One of its metabolites canrenone is also active and shows more pronounced anti-androgenic effects than parent drug

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VIP Nasal Spray in CIRS Neuro-Inflammation Ask a Clinician with Jacki Meinhardt, DNP, FNP Vasoactive Intestinal Peptide (VIP) is an endogenously occurring peptide hormone that plays a significant role in regulating the immune system and maintaining vascular tone