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Description
Researchers measure intracellular glutathione levels in preclinical studies using enzymatic recycling assays, HPLC with mass spectrometry, fluorescent probe-based assays, genetically encoded biosensors, and capillary electrophoresis
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Approach We explore the properties of glutathione metabolism in the liver by experimenting with a mathematical model of one-carbon metabolism, the transsulfuration pathway, and glutathione synthesis, transport, and breakdown
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