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Thus, the main analytical sample included 2574 participants (2363 from NESDA baseline and 211 siblings) with data on MDD diagnostic status, overall depression severity, and depressive symptoms profiles and at least one of the investigated metabolites

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Its role in fatty-acid oxidation is well established in basic science, and its been used clinically for decades in settings where mitochondrial function needs explicit support

NG, MG, and LP were involved in the critical revision and writing of the manuscript

It is unknown whether the findings are relevant for female mice

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