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This protective effect is independent of GSHs classical antioxidant activity and instead relies on its direct interaction with Cu + , which sequesters excess copper and prevents its aberrant binding to lipoylated proteins within the TCA cycle

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SH-SY5Y cells exhibit a distribution of VitB12 in the lysosomes, mitochondria, and cytosol, accounting for approximately 6%, 14%, and 80%, respectively

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Disruption of amino acid homeostasis by novel ASCT2 inhibitors involves multiple targets