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136 In addition, acquired astrocytopathies are prominent in hepatic encephalopathy (in which astrocytes lose their homoeostatic capabilities 137 ) and in neuromyelitis optica, in which the astrocyte protein, AQP4 is the subject of autoimmune attack, leading to dysfunction and death of astrocytes resulting in pronounced inflammation and degeneration of neural tissue

Both treatments often work in synergy to enhance overall therapeutic outcomes

To date, PCOS management strategies are primarily tailored to individual pathophysiological, clinical, and metabolic profiles

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USA 112 , 1373513740 (2015)

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