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Description
Efficacy and Safety of Adefovir Dipivoxil in Kidney Recipients, Hemodialysis Patients, and Patients with Renal Insufficiency
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This invention is directed towards development and identification of compounds that modulate/alter the way in which diverse viral pathogens interact with the host, so as to block or limit disease caused by these viruses and allow the host immune system to clear the viral pathogens
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Some examples of drugs that are eliminated by active tubular secretion include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see WARNINGS AND PRECAUTIONS ]
