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In Thailand and other Southeast Asian countries, despite the gradual enhancement of modern healthcare systems, traditional healers continue to play a vital role in community-based primary health services (Maneenoon et al., 2015)

PMCID: PMC5883860

10.1371/journal.pone.0113939 94 NagahisaT.YamaguchiS.KosugiS.HommaK.MiyashitaK.IrieJ.et al (2022)

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Intriguingly, the mode of cell death further dictates intercellular signaling

Silymarin (100 mg/kg) decreased cardiac fibrosis, collagen deposition, and dysfunction in diabetic mice, whereas silibinin used ERK1/2 MAPK signalling to control hypertrophic responses in cardiomyocytes (Wang et al., 2021)
