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In addition, pathways involving the cerebrospinal fluid (CSF), vasculature, and lymphatic system have been implicated in transporting molecules from the nasal cavity to the CNS [8]

Together, they target the structural repair mechanisms that conventional medicine largely ignores: collagen synthesis, connective tissue remodeling, angiogenesis at the injury site, and nerve repair

Importantly, these implications were observed without direct immunosuppression of specific cytokines such as TNF, implying a more regulatory mode of action
