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Alternatively, the GS-X GS- S(S )CN(CH 3 ) 2 can react with GSH, which further increase the intracellular DMDT concentration with the concomitant depletion of the GSH pool (Elskens and Penninckx, 1995a,1997)

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Halczuk KM, Boguszewska K, Urbaniak SK, Szewczuk M, Karwowski BT

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Therefore, they do not directly affect the transcription of target genes, but instead initiate a signaling cascade that is carried out by a molecule called a second messenger

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