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Boyle, K

Conclusion The production and elimination of ROS are in a dynamic equilibrium state, thereby maintaining the redox homeostasis

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doi: 10.1016/j.nbd.2022.105824 420 ZhangX.SongW

It was shown that TLR3 stimulation by the injection of viral mimic Poly(I: C) leads to a decrease in locomotor activity and exploratory rearing behavior in the open field (OF) test, as well as a decrease in water and food intake and 9 days of alternate day fasting exacerbate these effects (66)

164 In addition, hyperglycemia and other metabolic disorders such as dyslipidemia, inflammatory factors, excess IAPP and alterations in the gut microbiota, combine to contribute to IR and/or cell dysfunction through the common pathways of inflammation, ERS and oxidative stress (Fig