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Moreover, a preceding absence of cell polarity was found in GPx4fl/fl mice subjected to an RPE-specific adeno-associated virus (AAV)-Cre vector, which was alleviated by the Fer-1 (84)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Pesce M., La Fratta I., Paolucci T., Grilli A., Patruno A., Agostini F., Bernetti A., Mangone M., Paoloni M., Invernizzi M., et al

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However, despite these advances, traditional precision oncology approaches, which combine METTL3-14-WTAP activators and MAPK inhibitors, have not yet achieved satisfactory results in the treatment of thyroid cancer [28]

The main pharmacological effects and underlying mechanism of action of rutin contribute to its antioxidant capacity through the Nrf2/ARE and anti-inflammatory properties due to NF-B, COX-2, IL-6, and TNF- suppression