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Description
Adjunct drugs such as catechol-O-methyltransferase (COMT) and monoamine oxidase-B (MAO-B) inhibitors lack specificity to the central nervous system (CNS), have poor BBB permeability, and result in systemic side effects 15,16

doi: 10.1016/j.pharmthera.2017.02.021

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Injury to the skin and tissue

Lebrun, L

In preclinical IBD models using nanoparticle delivery, KPV reduces inflammation, normalizes epithelial barrier markers, and lowers cytokine load