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Accordingly, deletion of Gclc in B cells leads to a specific loss of MZB content but not FoB

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The novel mechanism by which 4-HNE inhibits NLRP3 is through its ability to directly bind to the critical domains of NLRP3, disrupting its interaction with the adapter protein NEK7, a key step in inflammasome activation, thereby preventing caspase-1 activation

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Evolution of the bile salt nuclear receptor FXR in vertebrates* s