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Moreover, USP7-mediated decrease of GATA1 poly-ubiquitylation was blocked by the USP7 inhibitors P5091 and P22077 (Figure 5C and Online Supplementary Figure S6B ), demonstrating that the enzymatic activity of USP7 is essential for the USP7-mediated deubiquitylation of GATA1

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doi: 10.1016/j.foodchem.2012.06.058 190

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