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It has been established that vitamin D modulates ongoing abnormal immune responses in chronic respiratory diseases and is shown to restrict bacterial and viral colonization into the lungs

Iodine imbalance further complicates this picture

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

However, large molecules, hydrophilic compounds, and many therapeutic agents, such as antibodydrug conjugate (ADC), are excluded, limiting the ability of systemic treatment to reach the brain

Treatment frequency and duration are discussed during consultation and tailored to individual response and goals

doi: 10.1007/s40257-013-0038-4