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The first phase of CNS response to acute focal TBI is the disruption of the blood-brain barrier and traumatic injury of parenchymal cells

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As discussed above, PKA also phosphorylates perilipin on the lipid droplet, resulting in changes that enhance stimulated lipolysis, including movement of perilipin away from the lipid droplet (21), perilipin-mediated remodeling of lipid droplets that increases the surface area available for lipolytic attack (75), and perilipin-mediated activation of HSL activity at the surface of the lipid droplet (84, 125)

[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Yajnik CS, Deshpande SS, Jackson AA, Refsum H, Rao S, Fisher DJ, Bhat DS, Naik SS, Coyaji KJ, Joglekar CV, et al