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The complication in using blood-flow measurements as an evaluation tool concerns the potential role of vascular insufficiency as a contributor to some forms of dementia

That point is especially well-reviewed [7]
"Efficacy of high-intensity laser therapy in the treatment of chronic neck pain: a randomized double-blind placebo-control trial." Lasers in Medical Science , 32(3):687-694

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New blood vessel formation could theoretically support tumor growth in those with existing malignancies