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Surgical procedures or conditions that affect the gut, such as gastric bypass surgery or celiac disease, can prevent intrinsic factors from binding to B12 and prevent the body from breaking it down before absorbing the vitamin
Also, it helps in the fight against some types of lung cancer

This results in a chiselled lower face appearance when you suck your cheeks in

You can also have the injection administered post-meal to reduce other side effects

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So, talk to your doctor if you take any of these
