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This capacity of FcRn antagonists to modulate the pharmacokinetics of other IgG-based Ab therapeutics was investigated in a phase I clinical trial (NCT04973566) addressing the effect of nipocalimab on the pharmacokinetics of the IgG Fc-fusion etanercept, which consists of the extracellular domains of tumor necrosis factor-alpha receptor 2 fused to an IgG1 Fc

Kumar et al., 2017)

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Taken together, our study adds to the literature describing perturbations in the endometrial, vaginal, cervical, and gut microbiotas of people with endometriosis

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CAS Number: 910463-68-2