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These findings suggest that retatrutide may offer broader cardiometabolic benefit beyond blood pressure reduction alone

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Eating disorders: Patients with a history of eating disorders should be assessed carefully before initiating any appetite-suppressing therapy, and psychological support should be considered as part of a holistic management plan

J Neuroendocrinol (1990) 2(6):797801

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Ensure adequate protein intake (at least 0.8 grams per pound of body weight), prioritize sleep, and avoid dramatic calorie restriction during the transition