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2019;20(13):pii: E3283
In this study, we investigated the role of KRAS constitutively active mutations in conferring platinum resistance in NSCLC
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
Thus, T was produced as a precursor in E2 biosynthesis long before AR evolved affinity for this steroid
This is more likely if spraying occurred in warm conditions, under bright light, or with too concentrated a solution
doi: 10.1016/j.scitotenv.2020.137581
