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As with any peptide, there could be risks, such as injection site reactions, water retention, or possible changes in insulin sensitivity

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[DOI] [PubMed] [Google Scholar] 39.Messner K.R., Imlay J.A

Nicotinamide (NAM) can also be obtained in the diet from the consumption of NAD and NADP, both of which are hydrolyzed to nicotinamide within the lumen of the small intestines