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The stomach produces it, which may be part of why it has such a broad cytoprotective profile: the gastric mucosa lives in a uniquely hostile environment and regenerates continuously
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This is different for folate receptors for which the affinity for folic acid is several-fold higher than for 5-methylTHF (65, 66)
That's the finding of a Dutch study published Jan
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doi:10.1155/2020/3267172 Gladman SJ, Huang W, Lim SN, et al
