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3.3 Reduced BDNF expression Brain-derived neurotrophic factor (BDNF) is an important neurotrophic substance in the central nervous system, which binds to Tropomyosin receptor kinase B (TrkB) receptors on postsynaptic neurons to promote synaptic strengthening and the formation of new synapses (56), consequently ensuring neuronal survival (57)
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A controversy circulated about the TMAO metabolite (associated with very high doses), but recent studies indicate that this effect is negligible at standard doses
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