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CCK is produced by enteroendocrine I cells found throughout the gastrointestinal tract

It has been used off-label by doctors for many years to help some patients manage their weight

Depending on your IBS subtype and symptoms, GLP-1s may either improve or aggravate gastrointestinal symptoms such as bloating, constipation, urgency or abdominal pain

Patient Assistance Programs Novo Nordisk and Eli Lilly offer assistance programs, though these typically don't work with government insurance like Medicaid

GLP-1 receptors (GLP-1R) are G-protein coupled receptors predominantly located in pancreatic cells, which underpins their role in glucose homeostasis

Eli Lilly Inc