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As discussed, PPAR nuclear receptors play a key role in insulin sensitivity

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For example, repeated dosing in rats revealed dose-dependent inflammation in hepatic Kupffer cells, but translatability to humans is uncertain due to interspecies variations in MPS activity [294]

[DOI] [PubMed] [Google Scholar] 174.Rossetti M., Spreafico R., Saidin S., Chua C., Moshref M., Leong J.Y., Tan Y.K., Thumboo J., van Loosdregt J., Albani S

According to preclinical research, silymarin reduces renal damage by having anti-inflammatory, anti-fibrotic, and antioxidant properties

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