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Chapuy L, Bsat M, Rubio M, Sarkizova S, Therrien A, Bouin M, et al

As a strong antioxidant, glutathione helps reduce free radicals that can activate tyrosinase, the enzyme that triggers melanin production

This is a stoichiometric process

It was observed in the last several years that HSCs have unique metabolic properties that promote a metabolically dormant and low cyclic state that enables stemness [39]
Of note, modeling these levels of hypoxia in vitro confirmed the expectation that oxidative metabolism would be maintained but underscored the potential for crosstalk among mechanisms, as hypoxia decreased amino acid uptake and mTORC1 activity [78]
Reduction of association between FUS/TLS mutants with U1-snRNP suggests a loss of activity in splicing regulation by FUS/TLS
