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Symptoms of Goat Polio Off feed/water Disorientation Staggering Circling Stargazing Convulsions Involuntary eye movements Temporary blindness Sudden death Note: Stargazing is characterized by the goats head thrown backwards due to rigid neck muscles

CTGF, connective tissue growth factor

In the presence of excess oxygen methylcobalamin is photolyzed at a rapid rate to yield aquocobalamin and formaldehyde as the major products

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The difference in side effect burden is real, and it is the primary reason the escalation process exists rather than starting everyone at the target dose