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In individual cases where the severity and frequency of the seizure disorder are such that the removal of medication does not pose a serious threat to the patient, discontinuation of the drug may be considered prior to and during pregnancy, although it cannot be said with any confidence that even minor seizures do not pose some hazard to the developing embryo or fetus [see Boxed Warning and Use in Specific Populations (8.1)]

The differentiation of MSCs toward the osteogenic lineage is tightly controlled by different molecular factors, including the bone morphogenic proteins (BMPs) [95, 96], and wingless-related integration site (WNT) pathway [97, 98]

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BMJ h6161 (2015)

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Well-optimized manufacturing processes can result in lower internal resistance and enhanced battery performance