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The pathogenesis of ALD involves multiple interconnected aging-related processes, including oxidative stress, inflammation, and mitochondrial dysfunction, all of which are regulated by SIRT1, a key modulator of cellular stress responses (Ramirez et al., 2017)

They come from the air we breathe, the food we eat, and even the stress of a busy workday

Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Buss S.S., Fried P.J., Pascual-Leone A
