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At the same time, SIRT1 deacetylates multiple transcription factors, such as Nrf2, promotes its entry into the nucleus and activates the expression of antioxidant stress genes, such as HO-1 and GPX4, the activation of which helps mitigate cell damage caused by ferroptosis

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In conditions like dysautonomia and Postural Orthostatic Tachycardia Syndrome (POTS), the ANS loses its ability to properly regulate heart rate, blood pressure, and vascular tone

Myth 5: Once you stop, your skin becomes darker

Medicine (Baltimore) 84:137146

shield skin from UV-induced damage