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Some drugs, including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs) are acid-inhibiting, impairing the release of dietary B12 from food proteins, thus producing risk of B12 deficiency (Lam et al., 2013)
Methods: Between January 2020 and the end of August 2024, 601 samples seized by the police and prosecutors office from the illegal market, intended for use as performance-enhancing drugs (PEDs), were tested at the Polish Official Medicines Control Laboratory
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NNMT inhibition increases intracellular NAD+ by blocking nicotinamide methylation, but the long-term metabolic consequences of sustained NNMT suppression
This is especially helpful for treating hypogonadism or supporting testicular function and sperm production during testosterone replacement therapy (TRT)
