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Certain acute/toxic exposures can overwhelm the ability of Cyb5R to reduce methemoglobin
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage

Interestingly these anti-oxidative properties were mainly found for the SPRR2 subfamily

[DOI] [PubMed] [Google Scholar] 124.Li W, et al

doi: 10.3389/fphar.2024.1483518 Received 20 August 2024 Accepted 07 November 2024 Published 19 November 2024 Volume 15 - 2024 Edited by Michael Heinrich, University College London, United Kingdom Reviewed by Fei Lin, The First Affiliated Hospital of Xinjiang Medical University, China Bing You Yang, Heilongjiang University of Chinese Medicine, China Updates Copyright 2024 Yao, Ma, Ran, Chen and He

Piccinin E, Cariello M, De Santis S, Ducheix S, Sabb C, NtambiJM, et al
