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Cytochrome c (CYCS), in conjunction with Apaf-1, forms the apoptosome in dATP/ATP-dependent manner, further recruiting procaspase 9 to initiate the caspase-processing cascade [77]

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found that a programmed cell death ligand 1 (PD-L1) inhibitor reduced tumor growth and increased oxidized lipids in cancer cells when studying mice with melanomas, suggesting that PD-L1 inhibitor induces ferroptosis (Wang et al., 2019)

doi: 10.1046/j.1365-2826.2001.00623.x 40 KamegaiJ.TamuraH.ShimizuT.IshiiS.SugiharaH.OikawaS
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