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KPV (Lysine-Proline-Valine): A C-terminal fragment of alpha-melanocyte-stimulating hormone (alpha-MSH)

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Other studies have demostrated that individuals with OPRM1 A118G polymorphism respond correctly to treatment with naltrexone, these findings can determine that the response to a pharmacotherapy of the patient requires less dose of naltroxone to produce the expected therapeutical effect, avoiding toxicity related to high doses of treatment, including death in the worst cases ( Taqi et al ., 2019 )

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