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PMID: 42284407 Nat Struct Mol Biol RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth

The meta-analysis was also limited by the small number of studies in MCI and AD studies reporting GSH in the brain
(4) Stey C et al., The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review, Eur Respir J, 2000, 16(2):253-62

Bilia AR, Bergonzi MC, Isacchi B, Antiga E, Caproni M

It is comprised of TRX and thioredoxin reductase (TRXR), which work in concert to maintain a redox balance in the cellular environment via disulfide reduction of target proteins

Therapeutic agents that regulate ROS levels to provide new ideas for glioma treatment are summarized in Table 2
