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Wu S, Shi H, Wu H, Yan S, et al

Ageing is believed to be a condition associated with free radical production (Busciglio & Yanker, 1995

In addition to direct chelation, DFO also regulates iron metabolic genes

HDAC6 regulates the acetylation of various non-histone proteins, affecting cellular redox balance, protein degradation and stress responses

Studies on patients with ischemic stroke suggest that high circulating IGF-I levels are associated with neurological recovery and a better functional outcome[339], probably due to its neuroprotective and pro-angiogenic effects
