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Welsh JL, Wagner BA, vant Erve TJ, et al

The absence of apoptosis in Spint1a-deficient larvae, together with the ability of Parp inhibitors to robustly reduce keratinocyte cell death in this model, led us to hypothesize that Parp1 overactivation in response to extensive ROS-mediated DNA damage would promote parthanatos cell death

10.1016/j.envexpbot.2018.11.013 Environ

Cell 185 , 44094427.e4418 (2022)

In other contexts where metabolic support is provided to retinal ganglion cells in glaucoma, inflammation persists ( e.g
