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The suppression can be severe and sometimes irreversible
Reactive oxygen species mostly affect the cells of kidneys proximal tubules, resulting in nephrotoxicity [69]
Matalka KZ, Al-Rawashdeh B, et al
102 BlancoIAstudilloADominguezFJanciauskieneSCarcabaVGalloCet al
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Moreover, gut microbiota-derived metabolites, including D-amino acids and reactive oxygen species, contribute directly to glomerular and tubular dysfunction by promoting oxidative stress and insulin resistance (Nagase et al., 2022)
